Which histology is considered a central primary lung cancer in the material?

Which histology is considered a central primary lung cancer in the material?

• A. Squamous cell carcinoma
• B. Adenocarcinoma
• C. Carcinoid
• D. Large cell carcinoma

Answer: (A)

Central tumors arise from the larger airways, especially the bronchi. Squamous cell carcinoma is the classic central lung cancer because it originates in the bronchial epithelium and tends to grow as a central mass near the hilum, often related to smoking. This central location contrasts with adenocarcinoma, which more commonly forms peripheral nodules from glandular-type cells in the lung tissue, and with large cell carcinoma, which is also usually peripheral. Carcinoid tumors can be central in some cases, but among these options, squamous cell carcinoma best fits the typical central primary lung cancer pattern.

Central tumors arise from the larger airways, especially the bronchi. Squamous cell carcinoma is the classic central lung cancer because it originates in the bronchial epithelium and tends to grow as a central mass near the hilum, often related to smoking. This central location contrasts with adenocarcinoma, which more commonly forms peripheral nodules from glandular-type cells in the lung tissue, and with large cell carcinoma, which is also usually peripheral. Carcinoid tumors can be central in some cases, but among these options, squamous cell carcinoma best fits the typical central primary lung cancer pattern.